1281060-70-5
1281060-70-5
Chemical Structure
CBD3063
- CAS No.: 1281060-70-5
- Formula:C16H25N5O2
- Molecular Weight:319.40
InChIKey: SYEHSRIUFPKYNX-UHFFFAOYSA-N
SMILES: O=C(N1CCCC(C1)NC(C)=O)NCCCNC2=NC=CC=C2
Biological Activity: CBD3063 is a selective modulator of collapsin response mediator protein 2 (CRMP2). CBD3063 uncouples Cav2.2 from CRMP2. CBD3063 reverses neuropathic and inflammatory pain by reducing membrane expression of CaV2.2[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CBD3063 | 99.75% | CBD3063 is a selective modulator of collapsin response mediator protein 2 (CRMP2). CBD3063 uncouples Cav2.2 from CRMP2. CBD3063 reverses neuropathic and inflammatory pain by reducing membrane expression of CaV2.2. | ||||||||||||||||||||
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References
- [1]. Gomez K, et, al. A peptidomimetic modulator of the CaV2.2 N-type calcium channel for chronic pain. Proc Natl Acad Sci U S A. 2023 Nov 21;120(47):e2305215120. [Content Brief]
- [2]. Allen HN, et, al. Uncoupling the CRMP2-CaV2.2 Interaction Reduces Pain-Like Behavior in a Preclinical Joint-Pain Model. J Pain. 2024 Sep 2:104664. [Content Brief]
Keywords
