1290133-16-2
1290133-16-2
Chemical Structure
Lu AF11205
- CAS No.: 1290133-16-2
- Formula:C17H16N2OS
- Molecular Weight:296.39
IUPAC Name: (2-(phenylethynyl)thiazol-5-yl)(piperidin-1-yl)methanone
InChIKey: RKNXXSOFHBIZJU-UHFFFAOYSA-N
SMILES: O=C(N1CCCCC1)C2=CN=C(S2)C#CC3=CC=CC=C3
Biological Activity: Lu AF11205 is a mGlu5 receptor positive allosteric modulator with activity modulating mGlu5 receptor activity. Optimization of Lu AF11205 resulted in a series of potent fused thiazole analogs whose structures and activities were influenced by substituents and which could affect receptor function in cell lines expressing mGlu5 receptors.
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Lu AF11205 | Lu AF11205 is a mGlu5 receptor positive allosteric modulator with activity modulating mGlu5 receptor activity. Optimization of Lu AF11205 resulted in a series of potent fused thiazole analogs whose structures and activities were influenced by substituents and which could affect receptor function in cell lines expressing mGlu5 receptors. | |||||||||||||||||||||
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Keywords
