130222-84-3
130222-84-3
Chemical Structure
5-O-(tert-Butyldiphenylsilyl)-2,3-isopropylidene-D-ribonolactone
- CAS. Nr.: 130222-84-3
- Formula:C24H30O5Si
- Molecular Weight:426.58
IUPAC Name: (3aR,6R,6aR)-6-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyldihydrofuro[3,4-d][1,3]dioxol-4(3aH)-one
InChIKey: DPXUCVYKYWELST-NJDAHSKKSA-N
SMILES: O=C1[C@H](OC(C)(C)O2)[C@H]2[C@@H](CO[Si](C3=CC=CC=C3)(C(C)(C)C)C4=CC=CC=C4)O1
Biological Activity: 5-O-(tert-Butyldiphenylsilyl)-2,3-isopropylidene-D-ribonolactone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5-O-(tert-Butyldiphenylsilyl)-2,3-isopropylidene-D-ribonolactone | 5-O-(tert-Butyldiphenylsilyl)-2,3-isopropylidene-D-ribonolactone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
