1303515-33-4
Chemical Structure
11β-HSD1-IN-6
- CAS No.: 1303515-33-4
- Formula:C21H19ClN4O
- Molecular Weight:378.85
IUPAC Name: (4aR,9aS)-1-(1H-benzo[d]imidazole-6-carbonyl)-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-b]pyridine-6-carbonitrile hydrochloride
InChIKey: XBTNKMAQSPPTRX-PXPMWPIZSA-N
SMILES: O=C(C1=CC=C(N=CN2)C2=C1)N3[C@]4([H])[C@@](CCC3)([H])C5=CC(C#N)=CC=C5C4.Cl
Biological Activity: 11β-HSD1-IN-6 is a an 11β-HSD-1 inhibitor. The 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs) mediate the interconversion of the glucocorticoid (GC) corticosterone or cortisol to an inactive form, 11-dehydrocorticosterone (11-DHC) or Cortisone, respectively[1].
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11β-HSD1-IN-6 | 11β-HSD1-IN-6 is a an 11β-HSD-1 inhibitor. The 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs) mediate the interconversion of the glucocorticoid (GC) corticosterone or cortisol to an inactive form, 11-dehydrocorticosterone (11-DHC) or Cortisone, respectively. | |||||||||||||||||||||
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Keywords
