131353-66-7
Chemical Structure
Efrapeptin F
- CAS No.: 131353-66-7
- Formula:C82H141N18O16+
- Molecular Weight:1635.11
InChIKey: HAOHIZZZBGXUNW-TYMATEDWSA-O
SMILES: O=C([C@H]1N(CCCC1)C(C(C)(C)NC(C(C)(C)NC(CNC(CCNC([C@H](CC(C)C)NC(C(C)(C)NC(C(C)(C)NC([C@H]2N(CCCC2)C(C(C)(C)NC([C@H]3N(CCCC3)C(C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC(C)(C)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@](CC)(C)C(N[C@@H](CC(C)C)C[N+]4=C5N(CCC4)CCC5)=O)=O)=O)=O
Biological Activity: Efrapeptin F is a mitochondrial complex V inhibitor and cytotoxic agent with in vivo antitumor activity. Efrapeptin F induces cell death in glucose-limiting conditions, with preferential cytotoxicity to nutrient-deprived cancer cells under hypoxic conditions. Efrapeptin F can be used for the research of pancreatic cancer, prostate cancer, breast cancer, central nervous system cancer, colon cancer, lung cancer, melanoma, ovarian cancer, kidney cancer, stomach cancer[1].
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Efrapeptin F | Efrapeptin F is a mitochondrial complex V inhibitor and cytotoxic agent with in vivo antitumor activity. Efrapeptin F induces cell death in glucose-limiting conditions, with preferential cytotoxicity to nutrient-deprived cancer cells under hypoxic conditions. Efrapeptin F can be used for the research of pancreatic cancer, prostate cancer, breast cancer, central nervous system cancer, colon cancer, lung cancer, melanoma, ovarian cancer, kidney cancer, stomach cancer. | |||||||||||||||||||||
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Keywords
