1319207-44-7
Chemical Structure
CC0651
- CAS No.: 1319207-44-7
- Formula:C20H21Cl2NO6
- Molecular Weight:442.29
IUPAC Name: (2R,3S,4S)-5-(3',5'-dichloro-[1,1'-biphenyl]-4-yl)-2,3-dihydroxy-4-(2-methoxyacetamido)pentanoic acid
InChIKey: NTCBTNCWNRCBGX-YTQUADARSA-N
SMILES: ClC1=CC(Cl)=CC(C2=CC=C(C=C2)C[C@@H]([C@@H]([C@H](C(O)=O)O)O)NC(COC)=O)=C1
Biological Activity: CC0651 is an allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme. CC0651 potently (IC50=1.72 μM) inhibits the ubiquitination of p27Kip1, as confirmed by dose-response analysis.
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CC0651 | 98.83% | CC0651 is an allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme. CC0651 potently (IC50=1.72 μM) inhibits the ubiquitination of p27Kip1, as confirmed by dose-response analysis. | ||||||||||||||||||||
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Keywords