1330822-91-7
1330822-91-7
Chemical Structure
S 8849-1-d4 free base
Synonym(s): Tianeptine metabolite MC5-d4
- CAS No.: 1330822-91-7
- Formula:C19H17D4ClN2O4S
- Molecular Weight:412.92
InChIKey: BYPYVXCZPZLHBO-CQOLUAMGSA-N
SMILES: OC(CC([2H])([2H])C([2H])([2H])CNC1C2=CC=C(Cl)C=C2S(=O)(N(C3=CC=CC=C31)C)=O)=O
Biological Activity: S 8849-1-d4 (free base) (Tianeptine metabolite MC5-d4) is deuterium labeled S 8849-1 (free base). S 8849-1 (free base) (Tianeptine metabolite MC5) is a Tianeptine (HY-90003) metabolite that is found in plasma. The mean elimination half-lives of S 8849-1 (free base) is 7.53 h in rats. S 8849-1 (free base) is promising for research of antidepressants[1][2].
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S 8849-1-d4 free base | S 8849-1-d4 (free base) (Tianeptine metabolite MC5-d4) is deuterium labeled S 8849-1 (free base). S 8849-1 (free base) (Tianeptine metabolite MC5) is a Tianeptine (HY-90003) metabolite that is found in plasma. The mean elimination half-lives of S 8849-1 (free base) is 7.53 h in rats. S 8849-1 (free base) is promising for research of antidepressants. | |||||||||||||||||||||
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S 8849-1 free base | S 8849-1 (free base) (Tianeptine metabolite MC5) is a Tianeptine (HY-90003) metabolite that is found in plasma. The mean elimination half-lives of S 8849-1 (free base) is 7.53 h in rats. S 8849-1 (free base) is promising for research of antidepressants. | |||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Gaulier JM, et al. High-performance liquid chromatographic determination of tianeptine in plasma applied to pharmacokinetic studies. J Chromatogr B Biomed Sci Appl. 2000 Oct 10;748(2):407-14. [Content Brief]
