1350884-56-8
1350884-56-8
Chemical Structure
(3aR)-Selitrectinib
Synonym(s): (3aR)-LOXO-195
- CAS No.: 1350884-56-8
- Formula:C20H21FN6O
- Molecular Weight:380.42
IUPAC Name: (13E,14E,22R)-35-fluoro-6-methyl-7-aza-1(5,3)-pyrazolo[1,5-a]pyrimidina-3(3,2)-pyridina-2(1,2)-pyrrolidinacyclooctaphan-8-one
InChIKey: OEBIHOVSAMBXIB-RGUGMKFQSA-N
SMILES: FC1=CN=C(CCC(N2)C)C([C@](CCC3)([H])N3C(C=CN4N=C5)=NC4=C5C2=O)=C1
Biological Activity: (3aR)-Selitrectinib ((3aR)-LOXO-195) is an isform of Selitrectinib (HY-101977), which is a next-generation TRK kinase inhibitor, with IC50s of 0.6 nM and <2.5 nM for TRKA and TRKC, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
(3aR)-Selitrectinib | (3aR)-Selitrectinib ((3aR)-LOXO-195) is an isform of Selitrectinib (HY-101977), which is a next-generation TRK kinase inhibitor, with IC50s of 0.6 nM and <2.5 nM for TRKA and TRKC, respectively. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
