135219-43-1
135219-43-1
Chemical Structure
Poststatin
- CAS No.: 135219-43-1
- Formula:C26H47N5O7
- Molecular Weight:541.68
IUPAC Name: ((S)-3-((S)-2-((S)-2-amino-3-methylbutanamido)-3-methylbutanamido)-2-oxopentanoyl)-D-leucyl-L-valine
InChIKey: LRXVQHCIMZSTJH-WPVAHCMFSA-N
SMILES: OC([C@@H](NC([C@@H](CC(C)C)NC(C([C@@H](NC([C@@H](NC([C@@H](N)C(C)C)=O)C(C)C)=O)CC)=O)=O)=O)C(C)C)=O
Biological Activity: Poststatin is a pecific prolyl endopeptidase (PEP) inhibitor. Poststatin inhibits bradykinin-degrading enzymes in rat urine[1][2].
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Poststatin | Poststatin is a pecific prolyl endopeptidase (PEP) inhibitor. Poststatin inhibits bradykinin-degrading enzymes in rat urine. | |||||||||||||||||||||
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References
- [1]. T Aoyagi, et al. Poststatin, a new inhibitor of prolyl endopeptidase, produced by Streptomyces viridochromogenes MH534-30F3. I. Taxonomy, production, isolation, physico-chemical properties and biological activities. J Antibiot (Tokyo). 1991 Sep;44(9):949-55. [Content Brief]
- [2]. M Majima, et al. Poststatin, a novel inhibitor of bradykinin-degrading enzymes in rat urine. Eur J Pharmacol. 1993 Mar 2;232(2-3):181-90. [Content Brief]
