135308-74-6
135308-74-6
Chemical Structure
N,O-Didesmethylvenlafaxine
Synonym(s): NODVFX
- CAS No.: 135308-74-6
- Formula:C15H23NO2
- Molecular Weight:249.35
IUPAC Name: 4-(1-(1-hydroxycyclohexyl)-2-(methylamino)ethyl)phenol
InChIKey: MMSWXJSQCAEDLK-UHFFFAOYSA-N
SMILES: OC1=CC=C(C(C2(O)CCCCC2)CNC)C=C1
Biological Activity: N,O-Didesmethylvenlafaxine (NODVFX) is a metabolite of Venlafaxine (VFX; HY-B0196). Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor[1][2].
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N,O-Didesmethylvenlafaxine | N,O-Didesmethylvenlafaxine (NODVFX) is a metabolite of Venlafaxine (VFX; HY-B0196). Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. | |||||||||||||||||||||
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N,O-Didesmethylvenlafaxine-d3 | N,O-Didesmethylvenlafaxine-d3 is the deuterium labeled N,O-Didesmethylvenlafaxine (HY-138818). N,O-Didesmethylvenlafaxine (NODVFX) is a metabolite of Venlafaxine (VFX; HY-B0196). Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. | |||||||||||||||||||||
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References
- [1]. Gabriel Hancu, et al. Enantioselective analysis of venlafaxine and its active metabolites: A review on the separation methodologies. Biomed Chromatogr. 2021 Jan;35(1):e4874. [Content Brief]
- [2]. Bymaster FP, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80. [Content Brief]
