1354041-91-0
1354041-91-0
Chemical Structure
IWP-051
- CAS. Nr.: 1354041-91-0
- Formula:C17H11F2N5O2
- Molecular Weight:355.30
IUPAC Name: 5-fluoro-2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)pyrimidin-4(3H)-one
InChIKey: LIVYVCAUBHXIMI-UHFFFAOYSA-N
SMILES: O=C1NC(C2=NN(CC3=CC=CC=C3F)C(C4=NOC=C4)=C2)=NC=C1F
Biological Activity: IWP-051 is an agonist for soluble guanylate cyclase with an EC50 of 290 nM. IWP-051 stimulates the generation of cGMP, and exhibits the synergistic effect with NO. IWP-051 exhibits good pharmacokinetic characteristics in rats[1].
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IWP-051 | IWP-051 is an agonist for soluble guanylate cyclase with an EC50 of 290 nM. IWP-051 stimulates the generation of cGMP, and exhibits the synergistic effect with NO. IWP-051 exhibits good pharmacokinetic characteristics in rats. | |||||||||||||||||||||
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