1356020-03-5
Chemical Structure
Quinapril-d5 hydrochloride
Synonym(s): CI-906-d5 hydrochloride
- No. CAS: 1356020-03-5
- Formula:C25H26D5ClN2O5
- Molecular Weight:480.01
IUPAC Name: (S)-2-(((S)-1-ethoxy-1-oxo-4-(phenyl-d5)butan-2-yl)-L-alanyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride
InChIKey: IBBLRJGOOANPTQ-GOMJJGCLSA-N
SMILES: [2H]C1=C([2H])C([2H])=C([2H])C([2H])=C1CC[C@@H](C(OCC)=O)N[C@@H](C)C(N2[C@@H](CC3=CC=CC=C3C2)C(O)=O)=O.Cl
Biological Activity: Quinapril-d5 hydrochloride (CI-906-d5) is the deuterium labeled Quinapril hydrochloride. Quinapril hydrochloride (CI-906) is a prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications[1][2].
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Quinapril-d5 hydrochloride | Quinapril-d5 hydrochloride (CI-906-d5) is the deuterium labeled Quinapril hydrochloride. Quinapril hydrochloride (CI-906) is a prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. | |||||||||||||||||||||
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Quinapril hydrochloride (Standard) | ≥98% | Quinapril (hydrochloride) (Standard) is the analytical standard of Quinapril (hydrochloride). This product is intended for research and analytical applications. Quinapril (hydrochloride) (CI-906) is a proagent that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. | ||||||||||||||||||||
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Quinapril hydrochloride | 98.30% | Quinapril (hydrochloride) (CI-906) is a proagent that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Song, J.C. and C.M. White, Clinical pharmacokinetics and selective pharmacodynamics of new angiotensin converting enzyme inhibitors: an update. Clin Pharmacokinet, 2002. 41(3): p. 207-24. [Content Brief]
