137234-71-0
Chemical Structure
Voriconazole camphorsulfonate
Synonym(s): UK-109496 camphorsulfonate
- CAS No.: 137234-71-0
- Formula:C26H30F3N5O5S
- Molecular Weight:581.61
IUPAC Name: (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol ((1R,4S)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate
InChIKey: AMYMCJHOGKVJHB-CRFUWKMFSA-N
SMILES: O[C@@]([C@@H](C)C1=NC=NC=C1F)(CN2N=CN=C2)C(C(F)=C3)=CC=C3F.O=S(C[C@](C4=O)(CC[C@H]5C4)C5(C)C)(O)=O
Biological Activity: Voriconazole (UK-109496) camphorsulfonate is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole camphorsulfonate exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes[1][2].
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Voriconazole camphorsulfonate | Voriconazole (UK-109496) camphorsulfonate is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole camphorsulfonate exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes. | |||||||||||||||||||||
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