1374828-69-9

GNE0877 Chemical Structure
1374828-69-9

Chemical Structure

GNE0877

Synonym(s): DNL201

  • CAS No.: 1374828-69-9
  • Formula:C14H16F3N7
  • Molecular Weight:339.32

IUPAC Name: 2-methyl-2-(3-methyl-4-((4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1H-pyrazol-1-yl)propanenitrile

InChIKey: ZPPUMAMZIMPJGP-UHFFFAOYSA-N

SMILES: CC1=NN(C(C)(C)C#N)C=C1NC2=NC=C(C(F)(F)F)C(NC)=N2

Biological Activity: GNE0877 is a highly selective, orally active and brain-penetrant LRRK2 inhibitor with an IC50 of 3 nM and a Ki of 0.7 nM. GNE0877 can be used for the research of neuroscience[1].

Cat. No. Product Name Purity Description Pricing
HY-15796
GNE0877 99.81% GNE0877 is a highly selective, orally active and brain-penetrant LRRK2 inhibitor with an IC50 of 3 nM and a Ki of 0.7 nM. GNE0877 can be used for the research of neuroscience.
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Amount:

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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References