138039-33-5
138039-33-5
Chemical Structure
Leptosphaerodione
- CAS No.: 138039-33-5
- Formula:C21H22O5
- Molecular Weight:354.40
IUPAC Name: (E)-10-hydroxy-7-methoxy-3-(4-methylhex-2-en-2-yl)-1H-benzo[g]isochromene-8,9-dione
InChIKey: YIEXBFWEBRLCNL-WUXMJOGZSA-N
SMILES: OC1=C2C(C=C(C(C2=O)=O)OC)=CC3=C1COC(/C(C)=C/C(C)CC)=C3
Biological Activity: Leptosphaerodione, isolated from Remotididymella sp. Fungus, is a potent ubiquitin-proteasome system (UPS) inhibitor. Leptosphaerodione exhibits cytotoxicity in HeLa cells with IC50 value of 3.2 μM. Anti-tumor agent[1].
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Leptosphaerodione | Leptosphaerodione, isolated from Remotididymella sp. Fungus, is a potent ubiquitin-proteasome system (UPS) inhibitor. Leptosphaerodione exhibits cytotoxicity in HeLa cells with IC50 value of 3.2 μM. Anti-tumor agent. | |||||||||||||||||||||
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