1384082-96-5
1384082-96-5
Chemical Structure
(1α,1'S,4β)-Lanabecestat
Synonym(s): (1α,1'S,4β)-AZD3293; (1α,1'S,4β)-LY3314814
- CAS No.: 1384082-96-5
- Formula:C26H28N4O
- Molecular Weight:412.53
IUPAC Name: (1s,1'S,4R)-4-methoxy-5''-methyl-6'-(5-(prop-1-yn-1-yl)pyridin-3-yl)-3'H-dispiro[cyclohexane-1,2'-indene-1',2''-imidazol]-4''-amine
InChIKey: WKDNQONLGXOZRG-ZSQFBXSQSA-N
SMILES: NC(C(C)=N1)=N[C@]21C3=C(C=CC(C4=CC(C#CC)=CN=C4)=C3)C[C@]52CC[C@@H](OC)CC5
Biological Activity: (1α,1'S,4β)-Lanabecestat ((1α,1'S,4β)-AZD3293) a less active enantiomer of Lanabecestat. Lanabecestat is a potent, orally active and blood-brain barrier penetrating BACE1 inhibitor with a Ki of 0.4 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(1α,1'S,4β)-Lanabecestat | 96.01% | (1α,1'S,4β)-Lanabecestat ((1α,1'S,4β)-AZD3293) a less active enantiomer of Lanabecestat. Lanabecestat is a potent, orally active and blood-brain barrier penetrating BACE1 inhibitor with a Ki of 0.4 nM. | ||||||||||||||||||||
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(1α,1'S,4β)-Lanabecestat (Standard) | ≥98% | (1α,1'S,4β)-Lanabecestat (Standard) is the analytical standard of (1α,1'S,4β)-Lanabecestat (HY-100740C). This product is intended for research and analytical applications. (1α,1'S,4β)-Lanabecestat ((1α,1'S,4β)-AZD3293) a less active enantiomer of Lanabecestat. Lanabecestat is a potent, orally active and blood-brain barrier penetrating BACE1 inhibitor with a Ki of 0.4 nM. | ||||||||||||||||||||
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References
