1392202-91-3
1392202-91-3
Chemical Structure
VPC03090
- CAS No.: 1392202-91-3
- Formula:C19H31NO
- Molecular Weight:289.46
IUPAC Name: (1-amino-3-(3-octylphenyl)cyclobutyl)methanol
InChIKey: FXTVJTIVYXHEBU-UHFFFAOYSA-N
SMILES: OCC1(CC(C1)C2=CC=CC(CCCCCCCC)=C2)N
Biological Activity: VPC03090 is an orally active prodrug of S1P1/3 antagonist. VPC03090 is phosphorylated by sphingosine kinase 2 (SK2) to form its active form VPC03090-P. VPC03090 reduces tumor volume in mouse breast cancer models. VPC03090 can be used in research related to breast cancer[1][2].
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VPC03090 | VPC03090 is an orally active prodrug of S1P1/3 antagonist. VPC03090 is phosphorylated by sphingosine kinase 2 (SK2) to form its active form VPC03090-P. VPC03090 reduces tumor volume in mouse breast cancer models. VPC03090 can be used in research related to breast cancer. | |||||||||||||||||||||
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References
- [1]. Kennedy PC, et al. Characterization of a sphingosine 1-phosphate receptor antagonist prodrug. The Journal of pharmacology and experimental therapeutics. 2011 Sep;338(3):879-89. [Content Brief]
- [2]. Kornienko A, et al. Toward a Cancer Drug of Fungal Origin. Medicinal research reviews. 2015 Sep;35(5):937-67. [Content Brief]
Keywords
