1394011-91-6
1394011-91-6
Chemical Structure
UC2288
- CAS 番号: 1394011-91-6
- Formula:C20H18ClF6N3O2
- Molecular Weight:481.82
IUPAC Name: 1-(4-chloro-3-(trifluoromethyl)phenyl)-3-((1r,4r)-4-((5-(trifluoromethyl)pyridin-2-yl)oxy)cyclohexyl)urea
InChIKey: ISPSOOYSNVVMMB-MQMHXKEQSA-N
SMILES: O=C(N[C@H]1CC[C@H](OC2=NC=C(C(F)(F)F)C=C2)CC1)NC3=CC=C(Cl)C(C(F)(F)F)=C3
Biological Activity: UC2288 is a potent and orally active p21 attenuator (relatively selective activity for p21), which is synthesized based Sorafenib (HY-10201). UC2288 potently inhibits cancer cell growth by inducing apoptosis. UC2288 has no inhibition of VEGFR2 and Raf kinases even at 10 μM[1].
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UC2288 | 99.78% | UC2288 is a potent and orally active p21 attenuator (relatively selective activity for p21), which is synthesized based Sorafenib (HY-10201). UC2288 potently inhibits cancer cell growth by inducing apoptosis. UC2288 has no inhibition of VEGFR2 and Raf kinases even at 10 μM. | ||||||||||||||||||||
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