1396772-26-1

EPZ005687 Chemical Structure
1396772-26-1

Chemical Structure

EPZ005687

  • CAS No.: 1396772-26-1
  • Formula:C32H37N5O3
  • Molecular Weight:539.67

IUPAC Name: 1-cyclopentyl-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-6-(4-(morpholinomethyl)phenyl)-1H-indazole-4-carboxamide

InChIKey: ZOIBZSZLMJDVDQ-UHFFFAOYSA-N

SMILES: O=C(NCC1=C(C)C=C(C)NC1=O)C2=CC(C3=CC=C(CN4CCOCC4)C=C3)=CC5=C2C=NN5C6CCCC6

Biological Activity: EPZ005687 is a potent and selective inhibitor of EZH2 with Ki of 24 nM, and has 50-fold selectivity against EZH1 and 500-fold selectivity against 15 other protein methyltransferases.

Cat. No. Product Name Purity Description Pricing
HY-15555 		EPZ005687 99.46% EPZ005687 is a potent and selective inhibitor of EZH2 with Ki of 24 nM, and has 50-fold selectivity against EZH1 and 500-fold selectivity against 15 other protein methyltransferases.
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