1396772-26-1
1396772-26-1
Chemical Structure
EPZ005687
- CAS No.: 1396772-26-1
- Formula:C32H37N5O3
- Molecular Weight:539.67
IUPAC Name: 1-cyclopentyl-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-6-(4-(morpholinomethyl)phenyl)-1H-indazole-4-carboxamide
InChIKey: ZOIBZSZLMJDVDQ-UHFFFAOYSA-N
SMILES: O=C(NCC1=C(C)C=C(C)NC1=O)C2=CC(C3=CC=C(CN4CCOCC4)C=C3)=CC5=C2C=NN5C6CCCC6
Biological Activity: EPZ005687 is a potent and selective inhibitor of EZH2 with Ki of 24 nM, and has 50-fold selectivity against EZH1 and 500-fold selectivity against 15 other protein methyltransferases.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
EPZ005687 | 99.46% | EPZ005687 is a potent and selective inhibitor of EZH2 with Ki of 24 nM, and has 50-fold selectivity against EZH1 and 500-fold selectivity against 15 other protein methyltransferases. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
