1402931-70-7
Chemical Structure
eIF4A3-IN-11
- CAS No.: 1402931-70-7
- Formula:C29H28O9
- Molecular Weight:520.53
IUPAC Name: dimethyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3,3a,8b-tetrahydro-1H-cyclopenta[b]benzofuran-2,6-dicarboxylate
InChIKey: PFGXGRUGXUDDMN-VBIJGHLJSA-N
SMILES: COC1=CC=C([C@@]23OC4=CC(C(OC)=O)=CC(OC)=C4[C@]2(O)[C@@H]([C@@H]([C@H]3C5=CC=CC=C5)C(OC)=O)O)C=C1
Biological Activity: eIF4A3-IN-11 (compound 56) is a Silvestrol (HY-13251) analogue. eIF4A3-IN-11 interferes the assembling of eIF4F translation complex with EC50s of 0.2, 4 and 0.3 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-11 can be used for the research of human cancer pathogenesis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
eIF4A3-IN-11 | eIF4A3-IN-11 (compound 56) is a Silvestrol (HY-13251) analogue. eIF4A3-IN-11 interferes the assembling of eIF4F translation complex with EC50s of 0.2, 4 and 0.3 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-11 can be used for the research of human cancer pathogenesis. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
