1402931-72-9
Chemical Structure
eIF4A3-IN-10
- CAS No.: 1402931-72-9
- Formula:C29H29NO8
- Molecular Weight:519.54
IUPAC Name: methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-6-(methylcarbamoyl)-3-phenyl-2,3,3a,8b-tetrahydro-1H-cyclopenta[b]benzofuran-2-carboxylate
InChIKey: QGBWLAVVBBEGCQ-VBIJGHLJSA-N
SMILES: COC1=CC=C([C@@]23OC4=CC(C(NC)=O)=CC(OC)=C4[C@]2(O)[C@@H]([C@@H]([C@H]3C5=CC=CC=C5)C(OC)=O)O)C=C1
Biological Activity: eIF4A3-IN-10 (compound 58) is a Silvestrol (HY-13251) analogue. eIF4A3-IN-10 interferes the assembling of eIF4F translation complex with EC50s of 35 and 100 nM for myc-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-10 can be used for the research of human cancer pathogenesis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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eIF4A3-IN-10 | 97.87% | eIF4A3-IN-10 (compound 58) is a Silvestrol (HY-13251) analogue. eIF4A3-IN-10 interferes the assembling of eIF4F translation complex with EC50s of 35 and 100 nM for myc-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-10 can be used for the research of human cancer pathogenesis. | ||||||||||||||||||||
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Keywords
