14075-00-4
Chemical Structure
D-Ribofuranose1-dihydrogenphosphate
Synonym(s): Ribose 1-phosphate
- CAS No.: 14075-00-4
- Formula:C5H11O8P
- Molecular Weight:230.11
IUPAC Name: (3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl dihydrogen phosphate
InChIKey: YXJDFQJKERBOBM-SOOFDHNKSA-N
SMILES: O[C@H]1C(OP(O)(O)=O)O[C@H](CO)[C@H]1O
Biological Activity: D-Ribofuranose 1-dihydrogenphosphate (Ribose 1-phosphate) dicyclohexanamine is a pentose phosphate and serves as a key intermediate metabolite in the salvage synthesis pathway of purine and pyrimidine nucleotides. In nucleotide salvage synthesis, D-Ribofuranose 1-dihydrogenphosphate dicyclohexanamine directly "transfers" the ribosyl group from purine nucleosides to pyrimidine bases, acting as a hub molecule linking nucleoside/base metabolism with pentose phosphate metabolism[1][2].
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D-Ribofuranose1-dihydrogenphosphate | D-Ribofuranose 1-dihydrogenphosphate (Ribose 1-phosphate) dicyclohexanamine is a pentose phosphate and serves as a key intermediate metabolite in the salvage synthesis pathway of purine and pyrimidine nucleotides. In nucleotide salvage synthesis, D-Ribofuranose 1-dihydrogenphosphate dicyclohexanamine directly "transfers" the ribosyl group from purine nucleosides to pyrimidine bases, acting as a hub molecule linking nucleoside/base metabolism with pentose phosphate metabolism. | |||||||||||||||||||||
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References
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[1]. Mascia L, et al. Ribose 1-phosphate and inosine activate uracil salvage in rat brain. Biochimica et Biophysica Acta (BBA)-General Subjects. 1999 Oct 18;1472(1-2):93-8.
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[2]. Barankiewicz J, Henderson JF. Ribose 1-phosphate metabolism in Ehrlich ascites tumor cells in vitro. Biochim Biophys Acta. 1977 Dec 14;479(4):371-7.
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