141318-62-9
141318-62-9
Chemical Structure
LY 293284
- CAS No.: 141318-62-9
- Formula:C19H26N2O
- Molecular Weight:298.42
IUPAC Name: (R)-1-(4-(dipropylamino)-1,3,4,5-tetrahydrobenzo[cd]indol-6-yl)ethan-1-one
InChIKey: CKYZLYQSDNLGPT-HNNXBMFYSA-N
SMILES: CC(C1=C2C3=C(C=C1)NC=C3C[C@@H](C2)N(CCC)CCC)=O
Biological Activity: LY 293284 is a potent and selective 5-HT1A receptor agonist. LY 293284 results in a significant drop in core temperature and consumes more food in cholestasis rat induced by bile duct resection[1][2].
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LY 293284 | LY 293284 is a potent and selective 5-HT1A receptor agonist. LY 293284 results in a significant drop in core temperature and consumes more food in cholestasis rat induced by bile duct resection. | |||||||||||||||||||||
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References
- [1]. Marona-Lewicka D, et al. Aripiprazole (OPC-14597) fully substitutes for the 5-HT1A receptor agonist LY293284 in the drug discrimination assay in rats. Psychopharmacology (Berl). 2004;172(4):415-421. [Content Brief]
- [2]. Burak KW, et al. Increased midbrain 5-HT1A receptor number and responsiveness in cholestatic rats. Brain Res. 2001;892(2):376-379. [Content Brief]
Keywords
