1415030-78-2
1415030-78-2
Chemical Structure
RmlA-IN-1
- CAS. Nr.: 1415030-78-2
- Formula:C18H18N4O4S
- Molecular Weight:386.42
IUPAC Name: N-(6-amino-1-benzyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-N-methylbenzenesulfonamide
InChIKey: NTXAKLDOOQBMCR-UHFFFAOYSA-N
SMILES: CN(S(=O)(C1=CC=CC=C1)=O)C2=C(N(C(NC2=O)=O)CC3=CC=CC=C3)N
Biological Activity: RmlA-IN-1 (Compound 8a) is a potent inhibitor of glucose-1-phosphate thymidylyltransferase (RmlA) with an IC50 of 0.073 μM. RmlA-IN-1 influences monosaccharide l-Rhamnose biosynthetic pathway. RmlA-IN-1 affects bacterial cell wall permeability[1].
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RmlA-IN-1 | RmlA-IN-1 (Compound 8a) is a potent inhibitor of glucose-1-phosphate thymidylyltransferase (RmlA) with an IC50 of 0.073 μM. RmlA-IN-1 influences monosaccharide l-Rhamnose biosynthetic pathway. RmlA-IN-1 affects bacterial cell wall permeability. | |||||||||||||||||||||
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