1415559-41-9
1415559-41-9
Chemical Structure
MK-8245 Trifluoroacetate
- CAS No.: 1415559-41-9
- Formula:C19H17BrF4N6O6
- Molecular Weight:581.27
IUPAC Name: 2,2,2-trifluoroacetic acid compound with 2-(5-(3-(4-(2-bromo-5-fluorophenoxy)piperidin-1-yl)isoxazol-5-yl)-2H-tetrazol-2-yl)acetic acid (1:1)
InChIKey: LEBPCMXFQYATAK-UHFFFAOYSA-N
SMILES: O=C(CN1N=C(N=N1)C2=CC(N3CCC(CC3)OC4=CC(F)=CC=C4Br)=NO2)O.FC(C(O)=O)(F)F
Biological Activity: MK-8245 Trifluoroacetate is a potent, liver-targeted stearoyl-CoA desaturase (SCD) inhibitor, with IC50s of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with antidiabetic and antidyslipidemic efficacy[1].
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MK-8245 Trifluoroacetate | 98.45% | MK-8245 Trifluoroacetate is a potent, liver-targeted stearoyl-CoA desaturase (SCD) inhibitor, with IC50s of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with antidiabetic and antidyslipidemic efficacy. | ||||||||||||||||||||
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