1417342-67-6
Chemical Structure
CD08108
- CAS No.: 1417342-67-6
- Formula:C31H38N4O4
- Molecular Weight:530.67
IUPAC Name: (R)-N-(1-(3-(cyclopropylmethoxy)-3-(o-tolyl)azetidin-1-yl)-3-(4-methoxyphenyl)-1-oxopropan-2-yl)-3-(4-methyl-1H-imidazol-5-yl)propanamide
InChIKey: NIJVIWSFUPHAMB-MUUNZHRXSA-N
SMILES: O(CC1CC1)C2(CN(C([C@@H](CC3=CC=C(OC)C=C3)NC(CCC=4NC=NC4C)=O)=O)C2)C5=C(C)C=CC=C5
Biological Activity: CD08108 is a selective MC1R full agonist with an EC50 of 70 nM against hMC1R. CD08108 participates in the melanogenesis process. CD08108 promotes cell proliferation. CD08108 can be used in studies related to vitiligo, subcutaneous diseases and photosensitive diseases[1][2][3].
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CD08108 | CD08108 is a selective MC1R full agonist with an EC50 of 70 nM against hMC1R. CD08108 participates in the melanogenesis process. CD08108 promotes cell proliferation. CD08108 can be used in studies related to vitiligo, subcutaneous diseases and photosensitive diseases. | |||||||||||||||||||||
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- [1]. Boiteau J G, et al. Development of a Kilogram-Scale Synthesis of a Novel MC1R Agonist[J]. Organic Process Research & Development, 2015, 19(6): 646-651.
- [2]. Mun Y, et al. Melanocortin 1 Receptor (MC1R): Pharmacological and Therapeutic Aspects. Int J Mol Sci. 2023;24(15):12152. Published 2023 Jul 29. [Content Brief]
- [3]. Mun Y W, et al. Melanocortin 1 Receptor (MC1R): Potentials as therapeutic targets[J]. 2023.
Keywords
