1425803-45-7
Chemical Structure
Cyclooctyne-O-NHS ester
- CAS No.: 1425803-45-7
- Formula:C14H17NO5
- Molecular Weight:279.29
IUPAC Name: 2,5-dioxopyrrolidin-1-yl 2-(cyclooct-2-yn-1-yloxy)acetate
InChIKey: KSXCIPWSNSHGIM-UHFFFAOYSA-N
SMILES: O=C(ON1C(CCC1=O)=O)COC2C#CCCCCC2
Biological Activity: Cyclooctyne-O-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Cyclooctyne-O-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cyclooctyne-O-NHS ester | 95.0% | Cyclooctyne-O-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Cyclooctyne-O-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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Keywords