1425803-45-7

Cyclooctyne-O-NHS ester Chemical Structure
1425803-45-7

Chemical Structure

Cyclooctyne-O-NHS ester

  • CAS No.: 1425803-45-7
  • Formula:C14H17NO5
  • Molecular Weight:279.29

IUPAC Name: 2,5-dioxopyrrolidin-1-yl 2-(cyclooct-2-yn-1-yloxy)acetate

InChIKey: KSXCIPWSNSHGIM-UHFFFAOYSA-N

SMILES: O=C(ON1C(CCC1=O)=O)COC2C#CCCCCC2

Biological Activity: Cyclooctyne-O-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Cyclooctyne-O-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No. Product Name Purity Description Pricing
HY-126517
Cyclooctyne-O-NHS ester 95.0% Cyclooctyne-O-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Cyclooctyne-O-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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