1428903-07-4
Chemical Structure
5-(Aminomethyl)-2′,3′-O-(1-methylethylidene)-2-thiouridine
- CAS No.: 1428903-07-4
- Formula:C13H19N3O5S
- Molecular Weight:329.37
IUPAC Name: 5-(aminomethyl)-1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
InChIKey: LLYVIOOQSMCMDM-TURQNECASA-N
SMILES: OC[C@@H]1[C@@H](OC(C)(C)O2)[C@@H]2[C@H](N3C=C(CN)C(NC3=S)=O)O1
Biological Activity: 5-(Aminomethyl)-2′,3′-O-(1-methylethylidene)-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5-(Aminomethyl)-2′,3′-O-(1-methylethylidene)-2-thiouridine | 5-(Aminomethyl)-2′,3′-O-(1-methylethylidene)-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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