1429386-01-5
Chemical Structure
AM-8735
- CAS No.: 1429386-01-5
- Formula:C27H31Cl2NO6S
- Molecular Weight:568.51
IUPAC Name: 2-((2R,5R,6R)-4-((S)-2-(tert-butylsulfonyl)-1-cyclopropylethyl)-6-(3-chlorophenyl)-5-(4-chlorophenyl)-3-oxomorpholin-2-yl)acetic acid
InChIKey: ZTMSSDQFJNEUNG-WMMXXEOUSA-N
SMILES: O=C(N1[C@H](CS(=O)(C(C)(C)C)=O)C2CC2)[C@@H](CC(O)=O)O[C@H](C3=CC=CC(Cl)=C3)[C@H]1C4=CC=C(Cl)C=C4
Biological Activity: AM-8735 is a potent and selective MDM2 inhibitor with an IC50 of 25 nM.
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AM-8735 | AM-8735 is a potent and selective MDM2 inhibitor with an IC50 of 25 nM. | |||||||||||||||||||||
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Keywords