1431626-44-6
1431626-44-6
Chemical Structure
PF-06465603
- CAS No.: 1431626-44-6
- Formula:C22H25N5O5
- Molecular Weight:439.46
IUPAC Name: 2-(((1r,4r)-4-(2-amino-6-(6-methoxypyridin-3-yl)-4-methyl-7-oxopyrido[2,3-d]pyrimidin-8(7H)-yl)cyclohexyl)oxy)acetic acid
InChIKey: FYGAMXOBXPHZMN-SHTZXODSSA-N
SMILES: O=C(O)CO[C@@H]1CC[C@@H](N(C2=NC(N)=NC(C)=C2C=C3C4=CC=C(OC)N=C4)C3=O)CC1
Biological Activity: PF-06465603 is a highly potent and selective ATP-competitive kinase inhibitor and a class 1 PI3K and mTOR inhibitor. PF-06465603 is a metabolite of PF-04691502 with a terminal carboxylic acid structure[1].
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PF-06465603 | PF-06465603 is a highly potent and selective ATP-competitive kinase inhibitor and a class 1 PI3K and mTOR inhibitor. PF-06465603 is a metabolite of PF-04691502 with a terminal carboxylic acid structure. | |||||||||||||||||||||
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