1432660-47-3
1432660-47-3
Chemical Structure
AGI-6780
- CAS No.: 1432660-47-3
- Formula:C21H18F3N3O3S2
- Molecular Weight:481.51
IUPAC Name: N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide
InChIKey: CCAWRGNYALGPQH-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(C2=CSC=C2)C(NC(NC3=CC=CC(C(F)(F)F)=C3)=O)=C1)(NC4CC4)=O
Biological Activity: AGI-6780 that potently and selectively inhibits the tumor-associated mutant IDH2R140Q with IC50 of 23±1.7 nM. AGI-6780 is less potent against IDH2WT with IC50 of 190±8.1 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
AGI-6780 | 99.32% | AGI-6780 that potently and selectively inhibits the tumor-associated mutant IDH2R140Q with IC50 of 23±1.7 nM. AGI-6780 is less potent against IDH2WT with IC50 of 190±8.1 nM. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
