143675-79-0
Chemical Structure
G-Protein antagonist peptide
- CAS No.: 143675-79-0
- Formula:C57H64N12O9S
- Molecular Weight:1093.26
IUPAC Name: (S)-N1-((5S,8R,11R,14S,17R)-8,11-bis((1H-indol-3-yl)methyl)-14-benzyl-5-carbamoyl-18-(1H-indol-3-yl)-7,10,13,16-tetraoxo-2-thia-6,9,12,15-tetraazaoctadecan-17-yl)-2-((S)-5-oxopyrrolidine-2-carboxamido)pentanediamide
InChIKey: WSYRBHQWMXTCHQ-SFIKJRKMSA-N
SMILES: CSCC[C@@H](C(N)=O)NC([C@@H](CC1=CNC2=C1C=CC=C2)NC([C@@H](CC3=CNC4=C3C=CC=C4)NC([C@H](CC5=CC=CC=C5)NC([C@@H](CC6=CNC7=C6C=CC=C7)NC([C@H](CCC(N)=O)NC([C@H](CC8)NC8=O)=O)=O)=O)=O)=O)=O
Biological Activity: G-Protein antagonist peptide is the substance P-related peptide that inhibits binding of G proteins to their receptors. G-Protein antagonist peptide competitively and reversibly inhibits M2 muscarinic receptor activation of Gi or Go and inhibits Gs activation by β-adrenoceptors.
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G-Protein antagonist peptide | G-Protein antagonist peptide is the substance P-related peptide that inhibits binding of G proteins to their receptors. G-Protein antagonist peptide competitively and reversibly inhibits M2 muscarinic receptor activation of Gi or Go and inhibits Gs activation by β-adrenoceptors. | |||||||||||||||||||||
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