1436920-57-8
Chemical Structure
Tapencarium
Synonym(s): RZL-012; Utenpanium chloride
- CAS No.: 1436920-57-8
- Formula:C20H25Br2ClN2
- Molecular Weight:488.69
InChIKey: GYDHQSBIPOHCIM-UHFFFAOYSA-M
SMILES: BrC1=CC=C2C(C3=C(N2CCCCC[N+](C)(C)C)C=CC(Br)=C3)=C1.[Cl-]
Biological Activity: Tapencarium (RZL-012; Utenpanium chloride) is an injectable fat volume-reducing agent. Tapencarium irreversibly impairs cell membrane integrity, increases membrane permeability, induces elevated cytoplasmic calcium, alters mitochondrial membrane potential, and triggers necrosis. Tapencarium induces fat necrosis, inflammatory responses and fibrous tissue formation at the injection site. Tapencarium can be used in research related to submental fat excess and Dercum's disease[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Tapencarium | 99.53% | Tapencarium (RZL-012; Utenpanium chloride) is an injectable fat volume-reducing agent. Tapencarium irreversibly impairs cell membrane integrity, increases membrane permeability, induces elevated cytoplasmic calcium, alters mitochondrial membrane potential, and triggers necrosis. Tapencarium induces fat necrosis, inflammatory responses and fibrous tissue formation at the injection site. Tapencarium can be used in research related to submental fat excess and Dercum's disease. | ||||||||||||||||||||
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- [1]. Shridharani SM, et al. Efficacy and Safety of Tapencarium (RZL-012) in Submental Fat Reduction. Aesthetic surgery journal. 2023 Sep 14;43(10):NP797-NP806. [Content Brief]
- [2]. Blaugrund E, et al. Mode of Action of RZL-012, a New Fat-Reducing Molecule. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. 2021 Dec 01;47(12):1601-1605. [Content Brief]
Keywords
