1437321-24-8
1437321-24-8
Chemical Structure
CEP-40783
Synonym(s): RXDX-106
- CAS No.: 1437321-24-8
- Formula:C31H26F2N4O6
- Molecular Weight:588.56
IUPAC Name: N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide
InChIKey: FKCWHHYUMFGOPY-UHFFFAOYSA-N
SMILES: O=C(C1=CN(C(C)C)C(N(C2=CC=C(F)C=C2)C1=O)=O)NC3=CC=C(OC4=CC=NC5=CC(OC)=C(OC)C=C45)C(F)=C3
Biological Activity: CEP-40783 is a potent, selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively.
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CEP-40783 | 99.61% | CEP-40783 is a potent, selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively. | ||||||||||||||||||||
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CEP-40783 (Standard) | ≥98% | CEP-40783 (Standard) is the analytical standard of CEP-40783 (HY-100946). This product is intended for research and analytical applications. CEP-40783 is a potent, selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively. | ||||||||||||||||||||
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Keywords
