1446399-26-3
Chemical Structure
CENP-E-IN-1
- CAS No.: 1446399-26-3
- Formula:C30H27F4N5O4S
- Molecular Weight:629.63
IUPAC Name: N-(7-cyano-1,1-dioxido-6-(trifluoromethyl)-2,3-dihydrobenzo[b]thiophen-3-yl)-N-(2-(dimethylamino)ethyl)-3-(4-fluoro-3-methylphenyl)-5-methoxyimidazo[1,2-a]pyridine-2-carboxamide
InChIKey: LSBPCEAYWVLUDD-UHFFFAOYSA-N
SMILES: O=C(N(CCN(C)C)C(C1)C2=CC=C(C(C#N)=C2S1(=O)=O)C(F)(F)F)C3=C(N4C(OC)=CC=CC4=N3)C5=CC=C(C(C)=C5)F
Biological Activity: CENP-E-IN-1 is a CENP-E inhibitor. CENP-E-IN-1 acts as a Mitotic arrest inducer and Apoptosis inducer, which causes abnormal alignment of chromosomes on the metaphase plate, activates the spindle assembly checkpoint and triggers apoptosis. CENP-E-IN-1 exhibits anti-tumor activity in colorectal adenocarcinoma xenograft models. CENP-E-IN-1 can be used in cancer-related research[1].
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CENP-E-IN-1 | CENP-E-IN-1 is a CENP-E inhibitor. CENP-E-IN-1 acts as a Mitotic arrest inducer and Apoptosis inducer, which causes abnormal alignment of chromosomes on the metaphase plate, activates the spindle assembly checkpoint and triggers apoptosis. CENP-E-IN-1 exhibits anti-tumor activity in colorectal adenocarcinoma xenograft models. CENP-E-IN-1 can be used in cancer-related research. | |||||||||||||||||||||
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