146196-17-0
146196-17-0
Chemical Structure
N6-Dimethylamino methylidene-2’-deoxyisoguanosine
- CAS No.: 146196-17-0
- Formula:C13H18N6O4
- Molecular Weight:322.32
IUPAC Name: (Z)-N'-(9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-3,9-dihydro-2H-purin-6-yl)-N,N-dimethylformimidamide
InChIKey: FOSUWRSEKRWMFJ-RPRWACGHSA-N
SMILES: OC[C@@H]1[C@@H](O)C[C@H](N2C(NC(N=C3/N=C\N(C)C)=O)=C3N=C2)O1
Biological Activity: N6-Dimethylamino methylidene-2’-deoxyisoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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N6-Dimethylamino methylidene-2’-deoxyisoguanosine | N6-Dimethylamino methylidene-2’-deoxyisoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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