1469439-69-7
Chemical Structure
Cabamiquine
Synonym(s): DDD107498; DDD-498; M5717
- CAS No.: 1469439-69-7
- Formula:C27H31FN4O2
- Molecular Weight:462.56
IUPAC Name: 6-fluoro-2-(4-(morpholinomethyl)phenyl)-N-(2-(pyrrolidin-1-yl)ethyl)quinoline-4-carboxamide
InChIKey: BENUHBSJOJMZEE-UHFFFAOYSA-N
SMILES: O=C(C1=CC(C2=CC=C(C=C2)CN3CCOCC3)=NC4=CC=C(C=C41)F)NCCN5CCCC5
Biological Activity: Cabamiquine (DDD107498) is a potent and orally active antimalarial agent, inhibits multiple life-cycle stages of the parasite, with an EC50 of 1 nM against P. falciparum 3D7. Cabamiquine inhibits protein synthesis by targeting eEF2/CaMKIII, with an EC50 of 2 nM for WT-PfeEF2[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cabamiquine | 99.61% | Cabamiquine (DDD107498) is a potent and orally active antimalarial agent, inhibits multiple life-cycle stages of the parasite, with an EC50 of 1 nM against P. falciparum 3D7. Cabamiquine inhibits protein synthesis by targeting eEF2/CaMKIII, with an EC50 of 2 nM for WT-PfeEF2. | ||||||||||||||||||||
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Keywords
