147416-96-4
147416-96-4
Chemical Structure
Telenzepine dihydrochloride
- CAS No.: 147416-96-4
- Formula:C19H24Cl2N4O2S
- Molecular Weight:443.39
IUPAC Name: 3-methyl-4-(2-(4-methylpiperazin-1-yl)acetyl)-4,9-dihydro-10H-benzo[b]thieno[3,4-e][1,4]diazepin-10-one dihydrochloride
InChIKey: JTQJFSQQHGPLOX-UHFFFAOYSA-N
SMILES: O=C1C2=CSC(C)=C2N(C(CN3CCN(C)CC3)=O)C4=CC=CC=C4N1.[H]Cl.[H]Cl
Biological Activity: Telenzepine dihydrochloride is a selective and orally active muscarinic M1 receptor antagonist with a Ki of 0.94 nM. Telenzepine dihydrochloride inhibits gastric acid secretion and has antiulcer effects[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Telenzepine dihydrochloride | 99.57% | Telenzepine dihydrochloride is a selective and orally active muscarinic M1 receptor antagonist with a Ki of 0.94 nM. Telenzepine dihydrochloride inhibits gastric acid secretion and has antiulcer effects. | ||||||||||||||||||||
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References
- [1]. R Riedel, et al. Comparison of the gastric antisecretory and antiulcer potencies of telenzepine, pirenzepine, ranitidine and cimetidine in the rat. Digestion. 1988;40(1):25-32. [Content Brief]
- [2]. F L Christofi, et al. Neuropharmacology of the muscarinic antagonist telenzepine in myenteric ganglia of the guinea-pig small intestine. Eur J Pharmacol. 1991 Apr 3;195(3):333-9. [Content Brief]
- [3]. M Galvan, et al. Interaction of telenzepine with muscarinic receptors in mammalian sympathetic ganglia. Eur J Pharmacol. 1989 Aug 11;167(1):1-10. [Content Brief]
