149466-04-6
Chemical Structure
BE 24566B
Synonym(s): L-755,805
- CAS No.: 149466-04-6
- Formula:
- Molecular Weight:460.48
InChIKey: MDUGEFRGUDVHQH-XNMGPUDCSA-N
SMILES: OC(C(C(C1=C2O)=O)=C(C(C)(C1=CC(O)=C2)C)C=C3C[C@@]4(C)O5)=C3[C@@]5([H])C(C(O4)=CC(O)=C6)=C6C
Biological Activity: BE 24566B is a polyketide fungal metabolite originally isolated from S. violaceusniger. It is active against B. subtilis, B. cereus, S. aureus, M. luteus, E. faecalis, and S. thermophilus (MICs=1.56, 1.56, 1.56, 1.56, 3.13, and 3.13 μg/mL, respectively). BE 24566B is an endothelin (ET) receptor antagonist (IC50s=11 and 3.9 μM for ETA and ETB receptors, respectively).
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BE 24566B | BE 24566B is a polyketide fungal metabolite originally isolated from S. violaceusniger. It is active against B. subtilis, B. cereus, S. aureus, M. luteus, E. faecalis, and S. thermophilus (MICs=1.56, 1.56, 1.56, 1.56, 3.13, and 3.13 μg/mL, respectively). BE 24566B is an endothelin (ET) receptor antagonist (IC50s=11 and 3.9 μM for ETA and ETB receptors, respectively). | |||||||||||||||||||||
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Keywords
