149759-26-2
Chemical Structure
Pinokalant
Synonym(s): LOE-908
- CAS No.: 149759-26-2
- Formula:C41H48N2O9
- Molecular Weight:712.83
IUPAC Name: 2-(6,7-dimethoxy-3,4-dihydroisoquinolin-1-yl)-2-phenyl-N,N-bis(2,3,4-trimethoxyphenethyl)acetamide
InChIKey: PYWYBTRACMRUQV-UHFFFAOYSA-N
SMILES: O=C(C(C1=NCCC2=C1C=C(C(OC)=C2)OC)C3=CC=CC=C3)N(CCC4=CC=C(C(OC)=C4OC)OC)CCC5=CC=C(C(OC)=C5OC)OC
Biological Activity: Pinokalant is a broad-spectrum and non-selectivecation channel inhibitor. Pinokalant significantly reduces cortical infarct volume. Pinokalant o improves the metabolic and electrophysiologic status of the ischemic penumbra. Pinokalant reduces lesion size on magnetic resonance images in the acute phase following middle cerebral artery occlusion in rats. Pinokalant has the potential for the research of stroke. Pinokalant also shows anti-SARS-CoV-2 activity[1].
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Pinokalant | 99.09% | Pinokalant is a broad-spectrum and non-selectivecation channel inhibitor. Pinokalant significantly reduces cortical infarct volume. Pinokalant o improves the metabolic and electrophysiologic status of the ischemic penumbra. Pinokalant reduces lesion size on magnetic resonance images in the acute phase following middle cerebral artery occlusion in rats. Pinokalant has the potential for the research of stroke. Pinokalant also shows anti-SARS-CoV-2 activity. | ||||||||||||||||||||
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Keywords
