150493-09-7
Chemical Structure
CE-1037
Synonym(s): MDL 201,404YA
- CAS No.: 150493-09-7
- Formula:C36H42O12S2
- Molecular Weight:730.84
IUPAC Name: 3,3'-(((2,2'-(1,4-phenylene)bis(2-methylpropanoyl))bis(oxy))bis(4,1-phenylenesulfonyl))bis(2,2-dimethylpropanoic acid)
InChIKey: HVXFLNJFYRWDQU-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(OC(C(C2=CC=C(C(C(OC3=CC=C(S(=O)(CC(C(O)=O)(C)C)=O)C=C3)=O)(C)C)C=C2)(C)C)=O)C=C1)(CC(C)(C)C(O)=O)=O
Biological Activity: CE-1037 (MDL 201,404YA) is a selective inhibitor of human neutrophil elastase (HNE) (Ki: 0.45 nM). CE-1037 prevents the pulmonary hemorrhage induced by intratracheal instillation of HNE. CE-1037 can be used for research of pulmonary diseases, such as COPD[1].
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CE-1037 | CE-1037 (MDL 201,404YA) is a selective inhibitor of human neutrophil elastase (HNE) (Ki: 0.45 nM). CE-1037 prevents the pulmonary hemorrhage induced by intratracheal instillation of HNE. CE-1037 can be used for research of pulmonary diseases, such as COPD. | |||||||||||||||||||||
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Keywords