151489-04-2
151489-04-2
Chemical Structure
S 16317
- CAS No.: 151489-04-2
- Formula:C28H33Cl2N3O6
- Molecular Weight:578.48
IUPAC Name: 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-6-methyl-2-((2-(2-((pyridin-4-ylmethyl)amino)ethoxy)ethoxy)methyl)-1,4-dihydropyridine-3,5-dicarboxylate
InChIKey: ACRICECUZJTXPQ-UHFFFAOYSA-N
SMILES: O=C(OC)C1=C(NC(COCCOCCNCC2=CC=NC=C2)=C(C1C3=C(Cl)C(Cl)=CC=C3)C(OCC)=O)C
Biological Activity: S 16317 is an orally active dihydropyridine derivative with low calcium channel affinity (Ki: 0.55 μM). S 16317 inhibits P-gp mediated efflux of ADR. S 16317 overcomes multidrug resistance in tumor[1].
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S 16317 | S 16317 is an orally active dihydropyridine derivative with low calcium channel affinity (Ki: 0.55 μM). S 16317 inhibits P-gp mediated efflux of ADR. S 16317 overcomes multidrug resistance in tumor. | |||||||||||||||||||||
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