153420-96-3
153420-96-3
Chemical Structure
Atibeprone
Synonym(s): Lu 53439
- CAS No.: 153420-96-3
- Formula:C17H18N2O3S
- Molecular Weight:330.40
InChIKey: HQTNJPCZUQAYAB-UHFFFAOYSA-N
SMILES: O=C1OC2=C(C(C)=C1C)C=CC(OCC3=NN=C(C(C)C)S3)=C2
Biological Activity: Atibeprone (Lu 53439) is a selective MAO-B inhibitor. Atibeprone has antidepressant activity[1][2].
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Atibeprone | Atibeprone (Lu 53439) is a selective MAO-B inhibitor. Atibeprone has antidepressant activity. | |||||||||||||||||||||
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References
- [1]. Löscher W,et al. Inhibition of monoamine oxidase type A, but not type B, is an effective means of inducing anticonvulsant activity in the kindling model of epilepsy. J Pharmacol Exp Ther. 1999 Mar;288(3):984-92. [Content Brief]
- [2]. Chhajed M, et al. Synthesis of 5-arylidine amino-1,3,4-thiadiazol-2-[(N-substituted benzyol)]sulphonamides endowed with potent antioxidants and anticancer activity induces growth inhibition in HEK293, BT474 and NCI-H226 cells. Med Chem Res. 2014;23(6):3049-3064. [Content Brief]
Keywords
