153660-03-8
Chemical Structure
Sp-8-Br-cGMPS
- CAS No.: 153660-03-8
- Formula:C10H11BrN5O6PS
- Molecular Weight:440.17
IUPAC Name: 2-amino-8-bromo-9-((2R,4aR,6R,7R,7aS)-7-hydroxy-2-mercapto-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl)-1,9-dihydro-6H-purin-6-one
InChIKey: KRYIOQOBMVFLBO-DGCJZISUSA-N
SMILES: O=C(NC(N)=N1)C2=C1N(C(Br)=N2)[C@H]3[C@H](O)[C@H](O[P@]4(S)=O)[C@@H](CO4)O3
Biological Activity: Sp-8-Br-cGMPS is an analog of cGMP. Sp-8-Br-cGMPS is an agonist for cGMP-gated cation channels (CNG channels), with an EC50 of 106.5 μM. Sp-8-Br-cGMPS induces the currents, without the ability to stabilize the channel open state as a full agonist[1].
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Sp-8-Br-cGMPS | Sp-8-Br-cGMPS is an analog of cGMP. Sp-8-Br-cGMPS is an agonist for cGMP-gated cation channels (CNG channels), with an EC50 of 106.5 μM. Sp-8-Br-cGMPS induces the currents, without the ability to stabilize the channel open state as a full agonist. | |||||||||||||||||||||
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Keywords
