154413-61-3
154413-61-3
Chemical Structure
SB-209247
- CAS No.: 154413-61-3
- Formula:C23H19Cl2NO3S
- Molecular Weight:460.37
IUPAC Name: (E)-3-(6-(((2,6-dichlorophenyl)thio)methyl)-3-phenethoxypyridin-2-yl)acrylic acid
InChIKey: ZJLFOOWTDISDIO-ZRDIBKRKSA-N
SMILES: O=C(O)/C=C/C1=NC(CSC2=C(Cl)C=CC=C2Cl)=CC=C1OCCC3=CC=CC=C3
Biological Activity: SB-209247 is a selective, high affinity and orally active leukotriene B4 (LTB4) receptor antagonist with a Ki of 0.78 nM. SB-209247 blocks LTB4-induced Ca2+ mobilization with an IC50 of 6.6 nM. SB-209247 shows a potent anti-inflammatory activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SB-209247 | 99.33% | SB-209247 is a selective, high affinity and orally active leukotriene B4 (LTB4) receptor antagonist with a Ki of 0.78 nM. SB-209247 blocks LTB4-induced Ca2+ mobilization with an IC50 of 6.6 nM. SB-209247 shows a potent anti-inflammatory activity. | ||||||||||||||||||||
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References
Keywords
