154738-42-8
Chemical Structure
Mitemcinal
Synonym(s): GM 611
- CAS No.: 154738-42-8
- Formula:C40H69NO12
- Molecular Weight:755.98
IUPAC Name: (2S,4R,5R,8R,9S,10S,11R,12R)-5-ethyl-11-(((2S,3R,4S,6R)-3-hydroxy-4-(isopropyl(methyl)amino)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-9-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-methoxy-2,4,8,10,12,14-hexamethyl-6,15-dioxabicyclo[10.2.1]pentadec-1(14)-ene-3,7-dione
InChIKey: BELMMAAWNYFCGF-PZXAHSFZSA-N
SMILES: C[C@]1(O2)[C@]([C@H]([C@]([C@H](C(O[C@H](CC)[C@](OC)(C)C([C@@H](C)C2=C(C)C1)=O)=O)C)([H])O[C@@]3([H])C[C@](C)([C@@H](O)[C@H](C)O3)OC)C)([H])O[C@@]4([H])[C@@H]([C@H](C[C@@H](C)O4)N(C)C(C)C)O
Biological Activity: Mitemcinal (GM 611) is an oral motilin receptor agonist. Studies in rabbits and dogs have shown that it can promote defecation without causing severe diarrhea, increase stool weight without increasing water content in the rabbit constipation model, and reduce the time to first defecation in dogs. Mitemcinal may be a constipation suppressant due to its early onset and short duration of action[1].
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Mitemcinal | Mitemcinal (GM 611) is an oral motilin receptor agonist. Studies in rabbits and dogs have shown that it can promote defecation without causing severe diarrhea, increase stool weight without increasing water content in the rabbit constipation model, and reduce the time to first defecation in dogs. Mitemcinal may be a constipation suppressant due to its early onset and short duration of action. | |||||||||||||||||||||
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Keywords
