15486-33-6
15486-33-6
Chemical Structure
Kaempferol-7,4'-dimethyl ether
- CAS No.: 15486-33-6
- Formula:C17H14O6
- Molecular Weight:314.29
IUPAC Name: 3,5-dihydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one
InChIKey: KZBAXKKOXPLOBX-UHFFFAOYSA-N
SMILES: O=C1C(O)=C(C2=CC=C(OC)C=C2)OC3=CC(OC)=CC(O)=C13
Biological Activity: Kaempferol-7,4'-dimethyl ether is a PTP1B inhibitor, and also can inhibit the production of NO. Kaempferol-7,4'-dimethyl ether shows the inhibition rate of 46.1% at 100 μM. Kaempferol-7,4'-dimethyl ether inhibits PTP1B activity with IC50 value of 16.92 μM[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Kaempferol-7,4'-dimethyl ether | 98.42% | Kaempferol-7,4'-dimethyl ether is a PTP1B inhibitor, and also can inhibit the production of NO. Kaempferol-7,4'-dimethyl ether shows the inhibition rate of 46.1% at 100 μM. Kaempferol-7,4'-dimethyl ether inhibits PTP1B activity with IC50 value of 16.92 μM. | ||||||||||||||||||||
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References
- [1]. Teeratad, et al. Inhibition of nitric oxide production by compounds from Boesenbergia longiflora using lipopolysaccharide-stimulated RAW264.7 macrophage cells.[J]. Songklanakarin Journal of Science & Technology, 2013.
- [2]. To D-C, et al. PTP1B Inhibitory Flavonoids From Orthosiphon stamineus Benth. and Their Growth Inhibition on Human Breast Cancer Cells. Natural Product Communications. 2020,15(1).
