1557240-80-8
Chemical Structure
BNC375
- CAS No.: 1557240-80-8
- Formula:C19H23ClN2O3S
- Molecular Weight:394.92
IUPAC Name: 4-((1R,3R)-3-(((5-chloro-2-methoxyphenyl)amino)methyl)-2,2-dimethylcyclopropyl)benzenesulfonamide
InChIKey: LWWDCTBUJUEFDE-CRAIPNDOSA-N
SMILES: ClC1=CC=C(OC)C(NC[C@H]2C(C)(C)[C@@H]2C3=CC=C(S(N)(=O)=O)C=C3)=C1
Biological Activity: BNC375 is a potent, selective, and orally available type I positive allosteric modulator of α7 nAChRs with an EC50 of 1.9 μM. BNC375 exhibits good CNS-agent like properties and clinical candidate potential. [1].
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BNC375 | 99.62% | BNC375 is a potent, selective, and orally available type I positive allosteric modulator of α7 nAChRs with an EC50 of 1.9 μM. BNC375 exhibits good CNS-agent like properties and clinical candidate potential. . | ||||||||||||||||||||
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Keywords