1557337-03-7
1557337-03-7
Chemical Structure
Spire2-FMN2 PPI-IN-1
- CAS No.: 1557337-03-7
- Formula:C11H12FN3
- Molecular Weight:205.23
InChIKey: XMFFMFYGVXVIHV-UHFFFAOYSA-N
SMILES: FC1=CC=C2C(N=CC=C2NCCN)=C1
Biological Activity: Spire2/FMN2 PPI-IN-1 (Compound 13) is a selective inhibitory fragment targeting the Spire2-FMN2 interaction, with an IC50 of 62 μM. Spire2/FMN2 PPI-IN-1 has affinity for KIND2, with a Kd of 87.7 μM, and does not inhibit KIND1. Spire2/FMN2 PPI-IN-1 can be used for the development of chemical probes for the Spire2-FMN2 interaction[1].
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Spire2-FMN2 PPI-IN-1 | Spire2/FMN2 PPI-IN-1 (Compound 13) is a selective inhibitory fragment targeting the Spire2-FMN2 interaction, with an IC50 of 62 μM. Spire2/FMN2 PPI-IN-1 has affinity for KIND2, with a Kd of 87.7 μM, and does not inhibit KIND1. Spire2/FMN2 PPI-IN-1 can be used for the development of chemical probes for the Spire2-FMN2 interaction. | |||||||||||||||||||||
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References
Keywords
