156406-33-6
Chemical Structure
9-keto Fluprostenol
- CAS No.: 156406-33-6
- Formula:C23H27F3O6
- Molecular Weight:456.45
IUPAC Name: (Z)-7-((1R,2R,3R)-3-hydroxy-2-((R,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-en-1-yl)-5-oxocyclopentyl)hept-5-enoic acid
InChIKey: WWMXHYUXIKWXSR-AAHOZRAYSA-N
SMILES: O[C@H]1[C@@H]([C@H](C(C1)=O)C/C=C\CCCC(O)=O)/C=C/[C@H](COC2=CC=CC(C(F)(F)F)=C2)O
Biological Activity: 9-keto Fluprostenol is an analog of prostaglandin E2 (PGE2) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF2α and acts primarily through the FP receptor. Oxidation at C-9 of fluprostenol yields 9-keto fluprostenol. It is anticipated that this analog will have strong affinity for EP receptors and act as a PGE2 agonist.
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9-keto Fluprostenol | 9-keto Fluprostenol is an analog of prostaglandin E2 (PGE2) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF2α and acts primarily through the FP receptor. Oxidation at C-9 of fluprostenol yields 9-keto fluprostenol. It is anticipated that this analog will have strong affinity for EP receptors and act as a PGE2 agonist. | |||||||||||||||||||||
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Keywords
